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What special precautions should I follow?
Use a condom during sexual intercourse. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy.
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Drug Interactions
Inform your doctor if you are taking any of the following:
- Lithium (e.g., Lithane) or
- Methotrexate or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine)
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What is this Drug
Acyclovir is used to treat herpes infections of the skin, lip, and genitals; herpes zoster (shingles); and chickenpox. It does not cure herpes infections but decreases pain and itching and promotes he
aling.
Topical acyclovir does not prevent the recurrence of sores but may decrease pain and itching if applied when the earliest symptoms first appear. Oral acyclovir decreases the frequency
and severity of recurrent sores, but it is used only by people with severe herpes infections because of possible adverse effects.
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How should this medicine be used?
Genital herpes (initial): 200mg po q 4 hours 5 times/day X 10 days
Genital herpes (recurrent or suppressive therapy): 400mg 2 times/day for up to 12 months, then re-evaluate.
Herpes zoster: 80
0mg 5 times/day X 7-10 days
Sever HZV or complications: 5-10mg/kg IV q 8 hours X 7-10 days. Administer at constant rate over 1 hour.
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Side Effects
Oral: (GI side effects reduced if take with meals)
Short-term therapy: nausea/vomiting, diarrhea, headache, dizziness, fatigue, skin rash, edema. inguinal adenopahty, anorexia, leg pain, medicatio
n taste, sore throat.
Long-term: nausea/vomiting, diarrhea, headache, vertigo, insomina, irritability, depression, skin rash, acne. accelerated hair loss, arthralgia, fever, palpitations, sore thr
oat, muscle cramps, mestrual abnormalities, lyphadenopathy.
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Other medical problems
This medication should be used cautiously during pregnancy only if clearly needed. It is not known if this medication appears in breast milk. Consult with your doctor before breast-feeding.
Avoid s
exual activity while signs and symptoms of genital herpes are present to prevent infecting your partner. Inform your doctor if this medication does not appear to decrease the frequency or severity of
recurrent infections.
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